Effectiveness of sarolaner in the clinical management of furuncular myiasis in dogs naturally infested with Dermatobia hominis (Diptera: Cuterebridae)

Abstract Background The human botfly, Dermatobia hominis , is a common cause of furuncular myiasis in dogs Latin America. Lesions can be single or multiple, each harboring an individual larva, presented as erythematous nodule that causes pruritus and pain. Typical treatment consists sedation for removal larvae by surgical incision manual pressure. Medications to kill the larva before its extraction reduce inflammation discomfort provide less traumatic larval removal. Isoxazolines are broad-spectrum ectoparasiticides with larvicidal activity previously reported screwworm companion animals. aim this study was evaluate effectiveness sarolaner part clinical management caused D. larvae. Methods Ten short-haired mixed breed naturally infested were enrolled. Clinical diagnosis achieved observation skin nodules visualization motility through lesion orifice. Sarolaner administered at manufacturer recommended dose fleas ticks. reexamined 24 h post-treatment assessed viability Larvae removed digital compression identified hominis. Results Seventy-five retrieved from ten dogs. No live observed, demonstrating 100% efficacy sarolaner. Skin lesions healed 30 days new not observed. Conclusions seems effective myiasis, reducing presence facilitating safe Graphical abstract